Low doses: how fast does tolerance build used daily?

I'm taking Adrafinil mainly for holding back appetite. On a good day 50mg is enough, otherwise 100mg. I'm new so I suspect I'll need higher doses in the future. I've read tolerance buildup is slower than normal for afinils, is that true? Even for daily usage? Can substituting one afinil for another help reverse tolerance or are they too similar for that to work (I hate caffeine). Read More

3 thoughts on “Low doses: how fast does tolerance build used daily?

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  • Tolerance is going to differ by the individual; keeping a journal and being diligent about objectively documenting how you feel while dosing can help you find your ceiling, but the best way to mitigate this is to simply cycle off of any afinil regularly. I wouldn’t suggest trying to cycle different types of afinils. Like many opioids, afinils are structurally very similar to one another and I would assume any evidence that cycling reduces tolerance is anecdotal at best.

    I normally advise against caffeine use while taking afinils, but if you’re specifically looking for appetite regulation, try microdosing your afinils, while stacking with caffeine, L-Theanine, and ACV. This combination can be extremely effective for reducing cravings, while maintaining energy levels. Microdosing can also help with tolerance, and allow you to garner much more consistent results throughout the day.

    I typically do several long term fasts; anywhere from 5 to 20 days. During those fasts I would start the morning with a microdose of flmoda, 200mg caffeine, 200mg L-Theanine, 2tbsp of ACV, repeated about 6 hours later. On that regiment, I could sustain fasts for weeks at a time without issue. I no longer stack afinils, but this worked really well for me when I used them regularly.

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